I've been using these strings on my guitar for many-many years now.
Only now am I realizing that maybe, playing 12s in standard tuning is not the best idea.
These strings work quite well for something like Drop C or maybe even D Standard tuning. If you play in standard tuning, I would suggest looking at some lighter gauge strings. Hammer-ons and pull-offs on the 1st fret are quite difficult in standard tuning with these strings (or at least they were on my cheap Peavey), and that's what finally did me in to look towards lighter gauges for standard tuning.
All in all, great strings for the price, but do have a moment to think about what strings you're using right now and how much more tension these strings bring to the table.