I've been testing/using lots of Dimarzio's pickups during the past decade from humbuckers to singlecoils and I have to say that this one is amazing.
The sound is very close to a single coil but with the advantage of the noise less feature, bright and puncy. I use it on a solid body Basswood guitar in the neck position, and so far it is realy inspiring.
I love that "special sound" of it without extra noise.
Eq. wise, the bass are bright and sparkly, so no sin of muddiness in the neck position, the notes comes out very easy and defined.
the treble are clear and never to bright in my opinion. I've tested it on various settings from "jazzy clean to hard rock distortion style".
The Area 61 also works very well in combination of an medium output Humbucker.
Finaly, I do recommend this Pickup for any guitar player in need of that twangy/fenderish sound with no extra noise for various music style such as Clean jazzy, blues and hard rock.